Tecoland supplies high purity Cisplatin bulk Active Pharmaceutical Ingredient (API) produced by GMP facility. We custom package for orders ranging from milligram to bulk quantity. Welcome to contact us with your specific request.

The following information is provided for general information purposes ONLY.

Introduction of Cisplatin

Cisplatin  is chemotherapy that is given as a treatment for some types of cancer. It is most commonly used to treat testicular, bladder, lung, gullet, stomach and ovarian cancers.

Possible side effects of Cisplatin

Each person’s reaction to chemotherapy is unique. Some people have very few side effects, while others may experience more. The side effects described on this information will not affect everyone who is given cisplatin, and may be different if you are having more than one chemotherapy drug.

Nausea and vomiting There are now very effective anti-sickness drugs to prevent or greatly reduce nausea and vomiting. If they do occur they may begin a few hours after the treatment is given and last for up to a few days. If the sickness is not controlled, or continues, tell your doctor, who can prescribe other anti-sickness drugs which may be more effective.

kidneys may be affected Usually this does not cause any symptoms, and the effect is mild, but if the effect is severe the kidneys can be permanently damaged unless the treatment is stopped. For this reason your kidneys will be checked by a blood test before each treatment. Fluid will be given into the vein before and after the treatment to keep your kidneys working normally. You may be asked to measure and record what you drink and the amount of urine that you pass. If you do not pass the same amount or more urine than you usually do, it is important to tell your nurse or doctor. If necessary, you may be given medicine to help you to pass urine.

Lowered resistance to infection  Cisplatin can reduce the production of white blood cells by the bone marrow, making you more prone to infection. This effect can begin seven days after treatment has been given and usually reaches its lowest point 10–14 days after chemotherapy. Your blood cells will then increase steadily and will usually have returned to normal within 21–28 days.

Contact your doctor or the hospital straightaway if:

• Your temperature goes above 38ºC (100.5ºF)

• You suddenly feel unwell (even with a normal temperature)

Bruising or bleeding  Cisplatin can reduce the production of platelets (which help the blood to clot). Let your doctor know if you have any unexplained bruising or bleeding.

Anemia  While having treatment with cisplatin you may become anemic. This may make you feel tired and breathless.

Numbness or tingling in hands or feet This is due to the effect of cisplatin on nerves and is known as peripheral neuropathy. You may notice that you have difficulty doing up buttons or similar fiddly tasks. Tell your doctor if you notice any numbness or tingling in your hands or feet. The side effect usually disappears slowly a few months after the treatment ends.

Changes in hearing You may have tinnitus (ringing in the ears) and you may lose the ability to hear some high-pitched sounds. Again, this effect usually decreases when the treatment ends, although in a small number of cases it may be permanent. Tell your doctor if you notice any loss of hearing or tinnitus.

Temporary taste alterations A dietitian or specialist nurse at your hospital can give advice about ways of coping with this side effect.

Loss of appetite The dietitian or specialist nurse can give you tips on boosting your appetite, coping with eating difficulties and maintain weight.

Diarrhoea This can usually be easily controlled with medicine but let your doctor know if it is severe or continues. It is important to drink plenty of fluids if you have diarrhoea.

Allergic reaction Signs of an allergic reaction include skin rashes and itching, a high temperature, shivering, redness or darkening of the face, dizziness, a headache, breathlessness, anxiety and a need to pass urine. You will be monitored for any signs of an allergic reaction during the treatment. Tell your doctor or nurse if you have any of these.

Disclaimer:

Information on this page is provided for general information purposes. You should not make a clinical treatment decision based on information contained in this page without consulting other references including the package insert of the drug, textbooks and where relevant, expert opinion. We cannot be held responsible for any errors you make in administering drugs mentioned on this page, nor for use of any erroneous information contained on this page.