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Introduction of
Mesna
Mesna is detoxifying agent. It reduces the harmful effects of
certain metabolites (breakdown products) of the cancer
chemotherapy medicine ifosfamide. Mesna is used to prevent
bleeding in the bladder (hemorrhagic cystitis) during
chemotherapy with ifosfamide. Mesna is used to prevent
bleeding in the bladder during chemotherapy with ifosfamide.
Precaution while taking Mesna
Do not take mesna without first talking to your doctor if you
have had a previous allergic reaction to mesna or to another
medicine that contains sulfur
an autoimmune disorder such as rheumatoid arthritis, systemic
lupus erythematosus, or nephritis.
You may not be able to take mesna, or you may require a dosage
adjustment or special monitoring during treatment.
Mesna is in the FDA pregnancy category B. This means that it
is not expected to be harmful to an unborn baby. Do not take
mesna without first talking to your doctor if you are pregnant
or could become pregnant during treatment.
It is not known whether mesna passes into breast milk. Do not
take mesna without first talking to your doctor if you are
breast-feeding a baby.
Side Effects of
Mesna
Seek emergency medical attention or contact your healthcare
provider immediately if you experience any of the following
serious side effects:
-
an allergic reaction (difficulty breathing;
closing of the throat; swelling of the lips, tongue, or
face; or hives)
-
pink or red colored urine
Other less serious side effects may be more likely to occur.
Continue to take mesna, and contact your doctor if you
experience any of the following side effects:
-
nausea or
vomiting
-
decreased
appetite
-
stomach pain
-
diarrhea
-
dizziness flush
-
fever
-
sensitive skin
or skin rash
-
Paleness of the
skin
-
sleepiness
-
coughing or cold symptoms
-
pain, redness, or irritation at the injection
site
-
swelling or water retention
-
low blood
pressure
Disclaimer:
Information on this page is provided for general
information purposes. You should not make a clinical treatment
decision based on information contained in this page without
consulting other references including the package insert of
the drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
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