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Introduction of Tamoxifen Citrate
Tamoxifen Citrate is an anti-oestrogen drug, designed to counteract
the effects of oestrogen. It was developed over 30 years ago
and is now used widely to treat breast cancer. It is also used
to treat a variety of other conditions, including infertility.
Possible side effects of Tamoxifen
Citrate
Each person’s reaction to any medication is unique. Because
people react to drugs in different ways, it is impossible to
predict who is going to have side effects. Many women who take
Tamoxifen Citrate have no side effects, while others will experience
them.
Very rarely, if the side effects are severe, you may have to
stop taking Tamoxifen Citrate and a different drug may be prescribed.
Side effects are more common in premenopausal women, who may
develop menopausal side effects as a result of a lowered level
of oestrogen. The most common side effects, apart from nausea,
are hot flushes and sweats, particularly at night.
Flushes and sweats
Sometimes the flushes will gradually lessen over the first few
months but some women continue to have them for as long as
they take Tamoxifen Citrate. There are a number of ways to help to
reduce or control hot flushes and sweats. Some women find it
helpful to avoid or cut down on tea, coffee, nicotine and
alcohol.
Some women find that complementary therapies can help, and
your GP can give you details about obtaining these on the NHS.
If you find your own complementary therapist, make sure that
they are properly qualified and registered.
Sometimes other drugs can be prescribed to reduce hot flushes
and sweats. Recent research suggests that progesterone or some
types of antidepressant drugs may be helpful in controlling
this unpleasant side effect.
If
you are having troublesome hot flushes do not hesitate to
discuss possible treatments with your doctor. Your doctor may
be able to prescribe a different hormonal therapy instead.
Sometimes the hot flushes continue for a long time after you
have stopped taking Tamoxifen Citrate.
Nausea and indigestion
Feelings of sickness
(nausea) and indigestion are fairly common but can often be
relieved by taking your tablets with food or milk or at night.
Although nausea is quite common initially, it usually wears
off after a few weeks.
Weight gain
Some women notice that they gain weight while taking Tamoxifen Citrate
and this may be due to water retention.
Change in periods
Women who have not yet reached the menopause may notice that
their monthly periods change – they may become irregular,
lighter or sometimes stop altogether.
Some women also notice an increase in
vaginal discharge and itching of the vulva (the area
around the vagina).
Disclaimer:
Information on this page is provided for general
information purposes. You should not make a clinical treatment
decision based on information contained in this page without
consulting other references including the package insert of
the drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
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