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Introduction of
Thalidomide
Thalidomide was first marketed in Europe in the
late 1950's. It was used as a sleeping pill and to treat
morning sickness during pregnancy. At that time no one knew
thalidomide caused birth defects.
Thalidomide is not approved for general sale in
the United States. However, the Food and Drug Administration
allows it to be used in studies. These are studies of certain
severe or life threatening diseases where there may be no
other treatment.
The purpose of this study is to attempt to
treat your condition and to gather information about the
safety and the potential benefit of thalidomide.
Precaution of Taking Thalidomide
-
You must have a blood or urine pregnancy test
before starting treatment. Results of this test must show
that you are not pregnant. The tests should be done and
interpreted by your doctor. These tests must be repeated
every month while you are taking thalidomide and four weeks
after your last dose of thalidomide. More frequent pregnancy
tests may be needed if you have an irregular menstrual
period, vaginal bleeding, or if you miss a period.
Side effects of Thalidomide
If you develop a skin rash with or without a
fever, fast heart beat, or low blood pressure, immediately
stop taking thalidomide and contact your doctor.
Any side
effect should be reported to your doctor. The following list
contains additional side effects that may occur while you are
taking thalidomide:
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mood changes
-
dry mouth
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headache
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nausea
-
constipation
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increased
appetite
-
puffiness of
the face and limbs
-
dry skin
-
itching
-
irregular
menstrual period
-
low white
blood cell count
-
thyroid
problems
-
blood sugar
that is too high or low
-
slow heart
beat
Disclaimer:
Information on this page is provided for general
information purposes. You should not make a clinical treatment
decision based on information contained in this page without
consulting other references including the package insert of
the drug, textbooks and where relevant, expert opinion. We
cannot be held responsible for any errors you make in
administering drugs mentioned on this page, nor for use of any
erroneous information contained on this page.
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